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Journal Article 1

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2022 1

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dactinomycin (ACTD) 1

gestational trophoblastic neoplasia (GTN) 1

methotrexate (MTX) 1

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Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 276-284 doi: 10.1007/s11684-021-0855-4

Abstract: Patients were allocated to three initiated regimens: single-course methotrexate (MTX), single-course MTX+ dactinomycin(ACTD), and multi-course MTX (control arm).After further treatment with multi-course ACTD, the CR rate (93.3%) was similar to that of the controlFor the single-course MTX+ACTD arm, the CR rate was 46.7% by one course, which increased to 89.1% afterIt was similar to the CR rate by MTX and further ACTD in the control arm (89.1% vs. 95.2%, P=0.135

Keywords： gestational trophoblastic neoplasia (GTN)     methotrexate (MTX)     dactinomycin (ACTD)    

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Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course

Journal Article